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Blood coagulation tests - what is the lab result?

Blood coagulation tests - what is the lab result?


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After a major thrombosis, it is very important to find out the underlying causes, as subsequent therapies play a major role in the overall treatment. Unfortunately, the causes are not always addressed, especially if the predisposition is not the cause of the problem.

Blood coagulation tests - what is the lab result?This is when the thrombosis develops in association with another illness, so it requires lengthy examination. Certain examinations are necessary to obtain a more accurate picture of the patient's coagulation system. Which of these are the most important and what they cover, arrуl dr. Zsuzsannab Szélessy, head of the Thrombosis and Hematology Center, was consulted by a hematologist.

Blood platelet count

Blood platelet enzymes are activated when they attach to a broken outer wall, thereby triggering the formation of a blood clot cascade - that is, the formation of blood. Decreasing their numbers causes bleeding, but too high a risk of thrombosis.

Prothrombin Id

It is used for the detection of haemorrhagic disorders and for the control of certain haemorrhagic therapies. Prothrombin is a key player in blood coagulation and the time it takes to elucidate the time it takes for the prothrombin to be active and to eventually convert to thrombin and then the blood to clot.

INR - prothrombin activity

Regular INR testing is required for regional type coagulation. The INR is the international standardization value for prothrombin activity as a percentage. In the course of anticoagulant therapy, these values ​​are set between 2.5 and 4.5. Depending on the disease, whether lower or upper values ​​should be approached better Values ​​below 2 do not precede the preparation of high blood values. Values ​​above 4.5 may cause bleeding.

Activated Parcel Thromboplastin Idх (APTI)

Without coagulation, we do not get a complete picture of APTI, and there is a malfunction or lack of other coagulation factors, if only the INR is determined. In the majority of susceptible patients, APTI opening is a warning laboratory signal to look for malfunctioning clotting factor. Less rarely, however, the higher the value of APTI, the higher the value of APTI.

D-dimer

D-dimer is a substance formed during the coagulation process, a degradation product of fibrin. It is used primarily for the verification of severe thrombosis / pulmonary embolism, but it is also an important service in the follow-up of the condition. Its higher level indicates the presence of blood.

Thrombophilia examination

Studies on genetically predisposed thrombosis. There are several types, and within them we distinguish between hetero- and homozygous forms, depending on the fact that only one or both of them are affected by the defect. Thrombophilia testing is needed not only after thrombosis, but also if you have a family history of having a problem, or if you have a history of hormone depletion, Inactivity) Examination of these whites is also a part of the thrombophilia examination (Antithrombin III, Protein C and Protein S, because the abnormalities of these whites are also more predominantly rare).

Homocysteine

Homocysteine ​​is a rich amino acid that has a significant deleterious effect. It is mainly metabolised to folate and vitamins B6 and B12. If the amount of blood in the blood increases for some reason, it increases the risk of developing blood vessels (both in the vein and the art) - says dr. Zsuzsanna Szélessy, chief hematologist at the Thrombosis and Hematology Center.

What should I do if something goes wrong?

Once the laboratory has confirmed the difference (s), the therapist will decide what therapy is needed. Patients may need only to pay attention to their lifestyle, but it may also require prophylactic therapy, ie prophylactic therapy. Injection or tablet therapy may be required, depending on the clinical picture, for the duration of the patient's life, temporarily for up to 1 year, or only for certain thrombotic conditions (eg:). the patient and thrombophilia examination showed a serious difference, then they may need to seek medical treatment or change the dose of the medicine.
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